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Acoustoelectronic System for High Intensity Focused Ultrasonic Radiation Forming Aiming Nano- and Microsized Containers Opening

Authors: Petrov A. V., Petrov V. V., Lapin S. A., Mokrousov M. D., Gorin D. A.

Background and Objectives: The aim of the study is to develop a system intended to the controlled release of preparations that were encapsulated to micro- and nanochambers. The system also allows to implement the optoacoustical diagnostics of the object by means of short light pulse radiation with the successive processing of the appeared ultrasonic signal.

Prospects For Application of Upconversion Particles NaYF4:Er,Yb for Phototherapy

Authors: Sagaidachnaya E. A., Yanina I. Y., Kochubey V. I.

Background and Objectives: Functionalized upconversion particles allow for photodynamic and photothermal therapy of tumor with simultaneous temperature monitoring and visualization of the area of treatment. Upconversion particles can increase the depth of therapeutic effects due to the high penetration depth of the required excitation radiation. That is why they are a promising material for the combined phototherapy and simultaneous monitoring of biological tissue heating.

Optical Clearing as Method to Increase the Depth of Nanoparticles Detection in the Skin with OCT-Visualization

Authors: Zaytsev S. M., Bashkatov A. N., Tuchin V. V., Genina E. A.

Background and Objectives: Nanoparticles of titanium dioxide are now widely used both for the creation of sunscreen filters, and as carriers of drugs. One of the ways of transepidermal delivery of these nanoparticles to the dermis of the skin is their penetration into the hair follicles. However, optical control of the filling of follicles with nanoparticles is rather difficult due to strong light scattering in the skin.

On the Possibility of Stabilization of a Contracted State after Riboflavin/UV Cross-Linking of Collagenous Tissue in a Partially Dehydrated State

Authors: Shvachkina M. E.

Background and Objectives: The method of riboflavin/UV collagen cross-linking is widely used to strengthen the corneal stroma in the treatment of keratoconus and is of considerable interest as a possible method to improve the biomechanical property of the sclera in the treatment of myopia. Regarding the application of this method to the sclera, one of the important problems is the rapid decrease in the intensity of UV radiation due to scattering as it propagates into the tissue.

Application of Thermal Imaging Diagnostics in Assessment of Inflammatory Response after Sclerotherapy in Patients with Lower Limb Varicose Disease

Authors: Chabbarov R. G., Ostrovsky N. V., Skripal A. V., Sanbaev A. K., Usanov A. D., Mayskov D. I.

Background and Objectives: Sclerotherapy of the lower extremities veins refers to one of the promising methods of treating patients with varicose veins. However, at present, there are no effective methods for assessing the condition of sclerotic veins during sclerotherapy.