The depth of penetration and localization of magnetic microparticles in skin under action of magnetostatic field was studied experimentally. In the study magnetic powder made from intermetallic composition SmCo5 consisting of 37% of samarium and 63% of cobalt was used. Sizes of the particles varied in the range 3–5 μm. As a carrier propylene glycol was used. The experiments were carried out with human skin samples in vitro.