optical coherence tomography

Optical Clearing as Method to Increase the Depth of Nanoparticles Detection in the Skin with OCT-Visualization

Authors: Zaytsev S. M., Bashkatov A. N., Tuchin V. V., Genina E. A.

Background and Objectives: Nanoparticles of titanium dioxide are now widely used both for the creation of sunscreen filters, and as carriers of drugs. One of the ways of transepidermal delivery of these nanoparticles to the dermis of the skin is their penetration into the hair follicles. However, optical control of the filling of follicles with nanoparticles is rather difficult due to strong light scattering in the skin.

Optical Doppler Methods for the Measurements of Flow Velocities of Biological Liquids

Authors: Proskurin S. G., Kuskova N. А., Avsievich Т. I.

Background and Objectives: In this paper the key results obtained by the authors during the years of development of Doppler optical methods for quasi-elastic light scattering and coherence gating on biomedical liquids are presented. The research is focused on the sign sensitive velocity measurement and quantitative visualization of alternating and complex geometry flows using spectral approach to digital data processing of Doppler shift of the carrier frequency.

Influence of 40%-glucose Solution on a Human Corneal Structure

Authors: Orlova A. S., Bashkatov A. N., Genina E. A., Kolbenev I. O., Kamensky I. D., Kamenskikh T. G., Tuchin V. V.

Effective treatment of the patients with postoperative corneal edema is one of the actual problems in ophthalmology. In this paper results of complex monitoring of influence of 40%-glucose solution on the state of both normal and edematous cornea after a cataract phacoemulsification on the base of date of confocal microscopy and optical coherence tomography have been presented. It has been shown that the glucose solution induces a short-term swelling of the healthy cornea and dehydration of the edematous one, as well as optical clearing of the tissue in the both cases.