confocal microscopy

PlasmonResonance Gold Nanoparticles as Drug Carriers and Optical Labels for Cytological Investigations

Authors: Bibikova O. A., Staroverov S. A., Sokolov O. I., Dikman L. A., Bogatyrev V. A.

In this paper we report on the investigation of the influence of plasmon resonant gold nanoparticles (PRGNPs) and their complex with anticancer drug prospidin to the physiological functions (endocytosis, respiratory activity, viability) of tumor cell lines HeLa and SPEV2. We used the combination of several microscopic regimes to register the light scattering and fluorescence for visualization the cells and PRGNPs. The citratestabilized colloidal gold with average particle diameter 50 nm was used as plasmon resonant labels.

Influence of 40%-glucose Solution on a Human Corneal Structure

Authors: Orlova A. S., Bashkatov A. N., Genina E. A., Kolbenev I. O., Kamensky I. D., Kamenskikh T. G., Tuchin V. V.

Effective treatment of the patients with postoperative corneal edema is one of the actual problems in ophthalmology. In this paper results of complex monitoring of influence of 40%-glucose solution on the state of both normal and edematous cornea after a cataract phacoemulsification on the base of date of confocal microscopy and optical coherence tomography have been presented. It has been shown that the glucose solution induces a short-term swelling of the healthy cornea and dehydration of the edematous one, as well as optical clearing of the tissue in the both cases.