diabetes mellitus

Investigation of «Erythrocyte – Plasma» Complex in Native Human Blood Slide Using WhiteLight FullField Microinterferometry

Authors: Kalyanov A. L., Malinova L. I., Bogolyubova E. V., Smirnov I. V., Lychagov V. V., Ryabukho V. P.

Morphofunctional properties of erythrocytes in native blood slide of coronary heart disease patients are investigated using white light fullfield microinterferometry. Three dimensional images and surface profiles of complex «single RBC – surrounding blood plasma» are shown. Dynamic of slope angle of the plasma near the RBC during standardized intravenous glucose load is explored. The dynamic of patients with coronary heart disease is compared with one of patients with coronary heart disease and diabetes mellitus.

Optical Study of Blood Rheological Properties for Krushinsky – Molodkina Strain Rats with Diabetes Mellitus and Acute Disturbances of the Cerebral Circulation

Authors: Fadyukova O. Е., Lugovtsov A. Е., Priezzhev A. V., Koshelev V. B.

Background and Objectives: The aim of the study was to assess the hemorheological parameters for rats with experimental diabetes and acute disturbances of the cerebral circulation.

Applying Methods of Diffuse Light Scattering and Optical Trapping for Assessing Blood Rheological Parameters: Erythrocytes Aggregation in Diabetes Mellitus

Authors: Semenov A. N., Lugovtsov A. Е., Lee K., Fabrichnova A. А., Kovaleva Y. А., Priezzhev A. V.

Background and Objectives: Aggregation parameters of blood characterize red blood cells interaction processes which play a major role in the microcirculation regulation. It was shown that these parameters are significantly different in case of Diabetes Mellitus (DM) and therefore can be proposed as a novel parameter of the disease state and therapy efficiency.

Optimization of Phacoemulsification in Different Forms of the Cataract in the Patients with Diabetes Mellitus

Authors: Tishkov A. S., Kamenskikh T. G., Galanga V. A., Bucharskaya A. B., Maslyakova G. N., Bashkatov A. N., Genina E. A., Kochubey V. I., Burov A. M., Tuchin V. V.

In this work, human lens pathology in different forms of the cataract was studied. Two hundred twenty patients with a cataract (220 eyes) were included in the study. Morphological, immunohystological and immunocytochemical investigations of both lens capsule and substance with antibodies to α- (α-А and α-В), β-, and γ- crystallines were carried out. Diabetic patients revealed a more pronounced expression of α- and β-B crystallin compared with a group of patients with age-related cataracts. Correlation between composition of the crystallines in a lens and its density was demonstrated.